A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Helicobacter pylori infection is a basic risk factor for chronic gastritis, and gastric carcinoma. Pathogenesis of gastric maltoma is a multistep process. Mucosaassociated lymphoid tissue malt lymphomas are a relatively recently recognized subset of bcell nhls, and they are listed as extranodal marginal zone lymphomas according to the revised. Pdf duodenal maltoma with gastric outlet obstruction. The pathological diagnosis of gastric malt lymphoma can be reached by. Bhs guidelines for the treatment of marginal zone lymphomas. Download the pdf esmomagnitude of clinical benefit scale clinical practice guidelines consensus. Architectural effacement by atypical centrocytelike cells small cleaved follicular cells with abundant cytoplasm, that infiltrate around reactive b cell follicles in a marginal zone distribution with spread into the interfollicular area may invade epithelial structures to form lymphoepithelial lesions. Wotherspoon criteria combined with b cell clonality analysis by advanced polymerase chain reaction technology discriminates covert gastric marginal zone lymphoma from chronic gastritis m hummel, s oeschger, t f e barth, c loddenkemper, s b cogliatti, a marx, h. Eradication of h pylori by antibiotic treatment leads to regression of gastric malt lymphoma in around 75% of cases and has become established.
Il linfoma gastrico appartiene alla grande categoria dei linfomi non hodgkin a localizzazione extranodale primitiva. Always seek the advice of your own physician or other qualified health care professional regarding any medical questions or conditions. A widely used method to help distinguish between reactive and malignant lymphoid lesions is the analysis of rearranged antigen. Helicobacter pylorinegative gastric mucosa associated. An extranodal lymphoma composed of morphologically heterogeneous small bcells including marginal zone centrocytelike cells, cells resembling monocytoid cells, small lymphocytes, and scattered immunoblasts and centroblastlike cells there is plasma cell differentiation in a proportion of cases the infiltrate is in. Primary gastric lowgrade bcell lymphomas are neoplastic mimics of mucosa associated lymphoid tissue malt as exemplified by peyers patches in the terminal ileum. Malt lymphoma maltoma is a form of lymphoma involving the mucosa associated lymphoid tissue malt, frequently of the stomach, but virtually any. Nel 2012, ha rappresentato l8,5% dei casi di tumore negli uomini diventando il quarto. Marginal zone lymphomas of the malt type are a type of bcell neoplasms that involve extranodal tissues and have an indolent clinical behavior. Then, a strict endoscopic followup is recommended, with mul tiple biopsies taken twothree months after treatment, and subsequently, at least twice a year for two years, to. Primary thyroid lymphomas constitute up to 5% of all thyroid malignancies and can be divided into nonhodgkins lymphomas nhls of b and tcell types, as well as hodgkins lymphomas. Pathology outlines marginal zone lymphoma malttype. Get a printable copy pdf file of the complete article 1. Pathology outlines extranodal marginal zone lymphoma of.
Full text full text is available as a scanned copy of the original print version. Mucosaassociated lymphoid tissue, malt lymphoma, stomach, large. Links to pubmed are also available for selected references. Gastric malt lymphoma and helicobacter pylori medicina clinica. Infection with helicobacter pylori is an influential promoter of gastric lymphomagenesis initiation. A preliminary breath test or stool antigen test should be performed at least 4 weeks after the antibiotic treatment to document h. Gastric mucosaassociated lymphoid tissue lymphoma and. The risk of spontaneous perforation of a gastric malt lymphoma is 410%. Nel 1993 isaacson e collaboratori lhanno dimostrato anche sperimentalmente. Then, a strict endoscopic followup is recommended, with multiple biopsies taken 23 months after treatment, and subsequently, at least twice per year for 2 years, to monitor the histological. A patogenese do linfoma malt tecido linfoide associado a mucosa gastrico. Gastric mucosaassociated tissue lymphoma malt lymphoma is a rare mature bcell neoplasm associated with h.
Malt lymphoma maltoma is a form of lymphoma involving the mucosaassociated lymphoid tissue malt, frequently of the stomach, but virtually any. The content on the uptodate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Approximately 90% of gastric maltomas are h pylori positive. Architectural and immunophenotypic properties of the neoplastic cells suggest that they originate from maltderived marginal zone bcells. Users can purchase an ebook on diskette or cd, but the most popular method of getting an ebook is to purchase a downloadable file of the ebook or other reading material from a web site such as barnes and noble to be read from the users computer or reading device. Linfoma della zona marginale extranodale wikipedia. Wotherspoon criteria combined with b cell clonality. A consecutive series of eight patients with gastric malt lymphoma were.
773 447 1247 1221 564 195 580 136 394 955 1426 34 401 1337 238 768 445 869 388 876 989 141 463 919 1192 617 757 193 855 1109 1080 47 239